Impact
Report 2025

Advancing Health for Society

Find.
Build.
Scale.

In a healthcare landscape challenged by market complexities, regulatory barriers, and industry fragmentation, only 5% of healthtech inventions ever reach the patients they were designed to help. NLC is changing this by finding, building, and scaling transformative health technologies.

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We identify high-impact innovations, develop them into market-ready ventures, and ensure they reach the patients and professionals who need them most. As healthcare systems face rising costs, aging populations, and increasing chronic diseases, innovation is more crucial than ever.

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By collaborating with leading institutions, corporations, and medical experts, we turn groundbreaking ideas into life-changing solutions that improve healthcare worldwide.

2025 at a glance:
Happy society

Healthcare systems face growing financial and operational pressure. Aging populations and the rise of chronic disease are increasing demand for care, while shortages of healthcare professionals and persistent system inefficiencies place additional strain on already stretched services.

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Our ventures address this challenge by developing solutions that optimize treatment pathways, support earlier recovery, and make better use of clinical expertise - helping reduce the total cost of care while expanding healthcare system capacity.

This year’s numbers

In 2025, we sharpened our focus on long-term value creation, and continued backing high potential ventures, evaluating breakthrough technologies, and securing critical funding to accelerate early-stage healthcare innovation.

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Technologies assessed

1,500+

Funding raised by portfolio ventures

€46M

Active ventures in portfolio

Clinical trials initiated or advanced
by portfolio ventures

Our ventures
are designed for societal impact

For the fourth consecutive year, our portfolio companies completed a structured impact assessment. The results highlight strong potential for positive societal impact.

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94%

expect to reduce healthcare costs

84%

expect to reduce workforce requirements across the care pathway

90%

expect to ease the burden on caregivers

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Venture spotlight

With 66 active ventures, our portfolio is driving innovation in healthcare and creating lasting impact for patients and society.

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“We strive to make prostate cancer diagnosis quicker, more affordable, and less invasive by pairing artificial intelligence technology with ultrasound imaging.”
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Mark Bloemendaal
‍CEO, PCaVision

“Addressing bacterial infections and the growing threat of antimicrobial resistance is one of the most significant societal challenges ahead. The World Health Organisation has called it ‘the next pandemic’, and as populations age, the problem will only accelerate. Our technology directly confronts this challenge.”
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Richard van de Wateringen
‍CEO, IPD

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“Ultimately, our work could reduce the long-term healthcare burden and improve independence for patients with CMT2D and related neuromuscular conditions, offering hope where current therapies fall short.”
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Dr. Erik Storkebaum
‍Inventor, XtRNA Bio

“The true cost of sleep apnea lies in the progression of comorbidities and work absences. By providing a permanent solution, we significantly reduce the long-term burden on both the healthcare system and the economy.”

Steven Coughlin
‍CEO, Respiosa

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Measuring our impact

The actions of NLC lead to the creation of portfolio companies which have the potential to solve the world’s healthcare challenges, with society serving as the foundational theme for this year's report.

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Happy Society

Our ventures are set up to create lasting value for society by making healthcare more accessible and affordable. Across our portfolio, 100% of ventures expect to deliver positive societal impact, with 94% aiming to reduce healthcare costs, 84% to reduce overall FTE requirements, and 90% to ease caregiver burdens.

Happy Patients

Our ventures aim to improve patient wellbeing by enabling faster diagnoses, improved treatment outcomes, and better healthcare experiences. Across our portfolio, 100% of ventures anticipate a positive patient impact, with 78% expected to increase life expectancy, 89% to alleviate pain and discomfort, and 90% to reduce the emotional burden on patients.

Happy Workforce

Our ventures support healthcare professionals by reducing administrative and physical burdens and helping create safer, more sustainable work environments. Across our portfolio, 79% of ventures expect to make a positive impact on the healthcare workforce.

Happy Planet

Our ventures reduce healthcare's environmental footprint by improving care efficiency and lowering energy consumption and waste. Across our portfolio, 57% of ventures expect to make a positive environmental impact compared with current standards of care, and 41% indicate a neutral footprint.

A word by
our CEO

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"Health is the foundation of a resilient society. When care systems are strained, the impact is felt far beyond the clinic - rippling through families, workplaces, and entire nations.

At NLC, we turn breakthrough science into solutions that strengthen these systems and create lasting societal value.

The future of healthcare won’t build itself - let’s build it together."

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